04
December
2013

Special Lecture by Michael Gutnick (Koret School of Veterinary Medicine, The Hebrew University of Jerusalem Rehovot, Israel)

Title: "Sodium channels and excitibility of cortical neurons and their axons"

Michael Gutnick

Time and venue: 11.00 a.m. at the Lecture Hall of the Max Planck Institute for Brain Research, Max-von-Laue-Str. 4, 60438 Frankfurt am Main (Campus Riedberg)

Abstract: Axons are essential components of local cortical circuitry.  My talk will be about the variable properties of voltage-gated sodium channels in the different compartments of a neocortical neuron, as revealed by whole-cell and single channel electrophysiological recordings and by quantitative sodium imaging. I will discuss why spikes always seem to originate in the axon. I will also talk about sodium currents that do not rapidly inactivate and their functional significance,  and I will discuss the different mechanisms that underlie this phenomenon in the axonal vs. the somato-dendritic membrane.

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Dr. Arjan Vink
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