Special Lecture by Michael Gutnick (Koret School of Veterinary Medicine, The Hebrew University of Jerusalem Rehovot, Israel)
Title: "Sodium channels and excitibility of cortical neurons and their axons"
Time and venue: 11.00 a.m. at the Lecture Hall of the Max Planck Institute for Brain Research, Max-von-Laue-Str. 4, 60438 Frankfurt am Main (Campus Riedberg)
Abstract: Axons are essential components of local cortical circuitry. My talk will be about the variable properties of voltage-gated sodium channels in the different compartments of a neocortical neuron, as revealed by whole-cell and single channel electrophysiological recordings and by quantitative sodium imaging. I will discuss why spikes always seem to originate in the axon. I will also talk about sodium currents that do not rapidly inactivate and their functional significance, and I will discuss the different mechanisms that underlie this phenomenon in the axonal vs. the somato-dendritic membrane.
Dr. Arjan Vink
T: +49 69 850033-2900
M: +49 175 2647988