A Focus on Networks
Brain circuits can be considered at many different levels. These levels span the interests of the MPI for Brain Research. 

For example, the intracellular protein network present in synapses includes all essential features of circuits including connected elements, communication, regulation and feedback. In response to signals from other neurons in a circuit, synapses interpret their inputs and transform them into outputs.  Some inputs modify the intracellular network by modifying the local ionic and protein environment, resulting in a change in the synaptic response.

Neural networks are another fundamental unit of brain function: the brain computes (transforms) inputs (external, via senses, or internal, such as thoughts, memories etc) into adaptive outputs (motor behaviors, percepts etc), according to some rules, or families of rules, that most often emerge from its components and their interactions; interestingly, those rules can change with time, experience, or context. 

Our common goal is a mechanistic understanding of the components of these networks, of the structural and functional circuits which they form, of the computational rules which describe their operations, and ultimately, of their roles in driving perception and behavior. Our experimental focus is on all scales (in space and time) required to achieve this understanding. That is, some of our work focuses on networks of molecules in dendritic compartments, while other focuses on networks of interacting brain areas. This requires analyses at the molecular, cellular, multi-cellular, network and behavioral levels, with the full understanding that macroscopic phenomena (spatial patterns, dynamics) can be scale-dependent; thus, while essential, reductionist approaches are not always sufficient, emphasizing also the need for theory.



Upcoming Lectures and Events

23 January 2018

Special Lecture/NeuroBioTheory Lecture by Matthew Chalk (Institut de la Vision, Paris, France)

Title: "What do sensory neurons do? Relating theories of neural coding with the informatio... [more]

24 January 2018

Neuroscience Lecture by Susanne Schreiber (Humboldt-Universität zu Berlin, Institute for Theoretical Biology)

Title: "Temperature and co: tuning into a new dynamical regime of neurons”. [more]

30 January 2018

Special/NeuroBioTheory Lecture by Tatiana Engel (Cold Spring Harbor Laboratory, New York, USA)

Title: "Discovering dynamic computations in the brain from large-scale neural activity rec... [more]

21 February 2018

Neuroscience Lecture by Yiota Poirazi (Computational Biology Laboratory, Institute of Molecular Biology and Biotechnology, Heraklion, Crete)

Title t.b.a. [more]

21 March 2018

Neuroscience Lecture by Kay Tye (Dept. of Brain & Cognitive Sciences, MIT, Cambridge, USA)

Title t.b.a. [more]