Publications

fold faq

Year 2018

Segarra M, Aburto MR, Cop F, Llaó-Cid C, Härtl R, Damm M, Bethani I, Parrilla M, Husainie D, Schänzer A, Schlierbach H, Acker T, Mohr L, Torres-Masjoan L, Ritter M, Acker-Palmer A. “Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system.” Science. 2018 Aug 24;361(6404). pii: eaao2861.

Stefani J, Tschesnokowa O, Parrilla M, Robaye B, Boeynaems JM, Acker-Palmer A, Zimmermann H, Gampe K. ” Disruption of the Microglial ADP Receptor P2Y13 Enhances Adult Hippocampal Neurogenesis.” Front Cell Neurosci. 2018 May 17;12:134.

Dopeso H, Jiao HK, Cuesta AM, Henze AT, Jurida L, Kracht M, Acker-Palmer A, Garvalov BK, Acker T. “PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFa.” Cancer Res. 2018 Apr 1;78(7):1805-1819.

Beckert B, Acker-Palmer A, Volknandt W. “Ab42 oligomers impair the bioenergetic activity in hippocampal synaptosomes derived from APP-KO mice.” Biol Chem. 2018 Apr 25;399(5):453-465.

fold faq

Year 2017

Pfennig S, Foss F, Bissen D, Harde E, Treeck JC, Segarra M, Acker-Palmer A. “GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.” Cell Rep. 2017 Oct 3;21(1):84-96.

Laßek M, Weingarten J, Wegner M, Neupärtl M, Array TN, Harde E, Beckert B, Golghalyani V, Ackermann J, Koch I, Müller UC, Karas M, Acker-Palmer A, Volknandt W. “APP Deletion Accounts for Age-Dependent Changes in the Bioenergetic Metabolism and in Hyperphosphorylated CaMKII at Stimulated Hippocampal Presynaptic Active Zones.” Front Synaptic Neurosci. 2017 Jan 20;9:1.

fold faq

Year 2016

De Rossi P, Harde E, Dupuis JP, Martin L, Chounlamountri N, Bardin M, Watrin C, Benetollo C, Pernet-Gallay K, Luhmann HJ, Honnorat J, Malleret G, Groc L, Acker-Palmer A, Salin PA, Meissirel C. “Co-activation of VEGF and NMDA receptors promotes synaptic targeting of AMPA receptors.” Mol Psychiatry. 2016 Dec;21(12):1647.

Spiegler S, Kirchmaier B, Rath M, Korenke GC, Tetzlaff F, van de Vorst M, Neveling K, Acker-Palmer A, Kuss AW, Gilissen C, Fischer A, Schulte-Merker S, Felbor U. “FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations.” Mol Syndromol. 2016 Jul;7(3):144-52.

Depner C, Zum Buttel H, Bögürcü N, Cuesta AM, Aburto MR, Seidel S, Finkelmeier F, Foss F, Hofmann J, Kaulich K, Barbus S, Segarra M, Reifenberger G, Garvalov BK, Acker T, Acker-Palmer A. “EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance.” Nat Commun. 2016 Jul 29;7:12329.

Laßek M, Weingarten J, Wegner M, Mueller BF, Rohmer M, Baeumlisberger D, Arrey TN, Hick M, Ackermann J, Acker-Palmer A, Koch I, Müller U, Karas M, Volknandt W. “APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.” PLoS Comput Biol. 2016 Apr 19;12(4):e1004832.

De Rossi P, Harde E, Dupuis JP, Martin L, Chounlamountri N, Bardin M, Watrin C, Benetollo C, Pernet-Gallay K, Luhmann HJ, Honnorat J, Malleret G, Groc L, Acker-Palmer A, Salin PA, Meissirel C. “A critical role for VEGF and VEGFR2 in NMDA receptor synaptic function and fear-related behavior.” Mol Psychiatry. 2016 Dec;21(12):1768-1780.

Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN. “Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.” Acta Neuropathol. 2016 Feb;131(2):281-298.

fold faq

Year 2015

Bernardini A, Brockmeier U, Metzen E, Berchner-Pfannschmidt U, Harde E, Acker-Palmer A, Papkovsky D, Acker H, Fandrey J. “Measurement of ROS Levels and Membrane Potential Dynamics in the Intact Carotid Body Ex Vivo.” Adv Exp Med Biol. 2015;860:55-9.

Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD. “14-3-3? coordinates adipogenesis of visceral fat.” Nat Commun. 2015 Jul 29;6:7671.

Segarra M, Kirchmaier BC, Acker-Palmer A. “A vascular perspective on neuronal migration.” Mech Dev. 2015 Nov;138 Pt 1:17-25.

Weingarten J, Laßek M, Mueller BF, Rohmer M, Baeumlisberger D, Beckert B, Ade J, Gogesch P, Acker-Palmer A, Karas M, Volknandt W. “Regional Specializations of the PAZ Proteomes Derived from Mouse Hippocampus, Olfactory Bulb and Cerebellum.” Proteomes. 2015 May 13;3(2):74-88.

Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon SO, Segarra M, Eberhart CG, Acker-Palmer A, Tosato G. “EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.” Nat Commun. 2015 Mar 26;6:6576.

fold faq

Year 2014

Gampe K, Haverkamp S, Robson SC, Gachet C, Hüser L, Acker-Palmer A, Zimmermann H. (2014). “NTPDase2 and the P2Y1 receptor are not required for mammalian eye formation.” Purinergic Signal.

Henze AT, Garvalov BK, Seidel S, Cuesta AM, Ritter M, Filatova A, Foss F, Dopeso H, Essmann CL, Maxwell PH, Reifenberger G, Carmeliet P, Acker-Palmer A, Acker T. (2014). “Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.” Nature Communications. 5:5582.

Garvalov BK, Foss F, Henze AT, Bethani I, Gräf-Höchst S, Singh D, Filatova A, Dopeso H, Seidel S, Damm M, Acker-Palmer A, Acker T. (2014). “PHD3 regulates EGFR internalization and signalling in tumours.” Nature Communications. 5:5577.

Laßek M, Weingarten J, Acker-Palmer A, Bajjalieh SM, Muller U, Volknandt W. (2014). “Amyloid precursor protein knockout disminishes synaptic vesicle proteins at the presynaptic active zone in mouse brain.” Curr Alzheimer Res. 11(10):971-80.

Seiradake E, del Toro D, Nagel D, Cop F, Härtl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R. (2014). “FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.” Neuron. 84(2):370-85.

Bernardini A, Brockmeier U, Metzen E, Berchner-Pfannschmidt U, Harde E, Acker-Palmer A, Papkovsky D, Acker H, Fandrey J. (2014). “Type I cell ROS kinetics under hypoxia in the intact mouse carotid body ex vivo: a FRET-based study.” Am J Physiol Cell Physiol. 1;308(1):C61-7-

Gampe K, Stefani J, Hammer K, Brendel P, Pötzsch A, Enikolopov G, Enjyoji K, Acker-Palmer A, Robson SC, Zimmermann H. (2014). “NTPDase2 and purinergic signalling control progenitor cell proliferation in neurogenic niches of the adult mouse brain.” Stem Cells. 33(1), 253-264.

Geiger JC, Lipka J, Segura I,  Hoyer S,  Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC and Acker-Palmer A. (2014). “The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development.” Developmental Cell. 28, 381-393.  

Worzfeld T, Swiercz JM, Sentürk A,  Genz B, Korostylev A, Deng S,  Xia J, Hoshino M, Epstein JA, Chan A, Vollmar B, Acker-Palmer A, Kuner R and Offermanns S. (2014). "Genetic dissection of plexin signalling in vivo.” Proc Natl Acad Sci U S A. 111(6):2194-9.

Bodea G, Spille J-H, Abe P, Senturk Andersson A, Acker-Palmer A, Stumm R, Kubitscheck U, Blaess S. (2014). “Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.” Development. 141:661-673; doi:10.1242/dev.099937

fold faq

Year 2012

Sawamiphak S, Bethani I, Ritter M, Acker-Palmer A. (2012). “Ex vivo retinal explant cultures to study angiogenic responses.” The Textbook of Angiogenesis and Lymphangiogenesis. Methods and Applications. Editors: Zudaire E and Cuttitta F. pp 169-180.

Carrasco P, Sahún I, McDonald J, Ramírez S, Jacas J, Gratacós E, Sierra AY, Serra D, Herrero L, Acker-Palmer A, Hegardt FG, Dierssen M, Casals N. (2012). „Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.“ J Biol Chem. 287:21224-32.

fold faq

Year 2011

Doeppner, T.R., Bretschneider, E., Doehring, M., Segura, I., Sentürk, A., Acker-Palmer, A. Hasan, M.R., ElAli, A., Hermann, D., Bähr, M. (2011) “Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia”. Acta Neuropathologica 122:429-42.

Puri P, Acker-Palmer A, Stahler R, Chen Y, Kline D, Vijayaraghavan S. (2011). “Identification of testis 14-3-3 binding proteins by tandem affinity purification”. Spermatogenesis 1:354-365.

Senturk, A., Pfennig, S., Weiss, A., Burk, K. and Acker-Palmer, A. (2011) “EphrinBs are essential components of the Reelin pathway to regulate neuronal migration”. Nature, 472:356-60. Erratum Nature 478:274

Deutsch, G.B.,  Zielonka, E.M., Coutandin, D., Weber, T.A., Schäfer, B., Hannewald, J., Luh, L.M., Durst, F.G., Ibrahim, M., Hoffmann, J., Niesen, F.H., Sentürk, A., Kunkel, H., Brutschy, B., Schleiff, E., Knapp, S., Acker-Palmer, A., Grez, M., McKeon, F. and Dötsch, V. (2011) “DNA damage in oocytes induces an irreversible switch of the quality control factor TAp63α from dimer to tetramer”. Cell, 144:566-576.

fold faq

Year 2010

Sawamiphak, S., Ritter, M. and Acker-Palmer, A. (2010) “Preparation of retinal explant cultures to study ex vivo tip endothelial cell responses”. Nature Protocols 5, 1659 – 1665.

Bethani, I., Skånland, S.S., Dikic, I. and Acker-Palmer, A. (2010) “Spatial organization of transmembrane receptor signalling”. EMBO J , 29: 2677-2685.

Sawamiphak, S., Seidel, S., Essmann, C.L., Wilkinson, G., Pitulescu, M.E., Acker, T. and Acker-Palmer, A. (2010) “EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis” Nature 465, 487–491. *Co-corresponding

fold faq

Year 2008

Snow, A.J., Puri, P., Acker-Palmer, A., Bouwmeester, T., Vijayaraghavan, S. and Kline, D. (2008). Phosphorylation-Dependent Interaction of Tyrosine 3 Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein (YWHA) with PADI6 Following Oocyte Maturation in Mice. Biol. Reprod. 79, 337–347

Essmann, C.L., Martinez, E., Geiger, J., Zimmer, M., Traut, M., Stein, V., Klein, R. and Acker-Palmer, A. (2008) Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nature Neuroscience 11: 1035 – 1043

fold faq

Year 2007

Segura, I., Eβmann, C. L., Weinges, S. and Acker-Palmer, A. (2007). “Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation” Nature Neuroscience 10: 301-310.

fold faq

Year 2006

Angrand, P.O., Segura, I., Völkel, P., Ghidelli, S., Terry, R., Brajenovic, M., Vintersten, K., Klein, R., Superti-Furga G., Drewes, G., Küster, B., Bouwmeester, T. and Acker-Palmer, A. (2006) Transgenic mouse proteomics identifies new 14-3-3 associated proteins involved in cystoskeletal rearrangements and cell signaling, Molecular and Cellular Proteomics, 5: 2211-2227

fold faq

Year 2004

Bruhl, T., Urbich, C., Aicher, D., Acker-Palmer, A., Zeiher, A.M. and Dimmeler, S. (2004): Homeobox A9 transcriptionally regulates the EphB4 receptor in endothelial cell migration and tube formation. Circ Res 94: 743-751

fold faq

Year 2003

Palmer, A. and Klein, R. (2003) Multiple roles of ephrins in morphogenesis, neuronal networking, and brain function. Genes & Development 17: 1429-1450.

Zimmer, M., Palmer, A., Köhler, J. and Klein, R. (2003). Contact-mediated repulsion by ephrinB ligands and EphB receptors requires bi-directional endocytosis.  Nature Cell Biol  5: 869-78. (News and Views Nature Cell Biol  5: 851-53, Highlights Signalling Nature Reviews Molecular Cell Biology 4:753, Previews. Dev Cell 4: 536-7)

fold faq

Year 2002

Palmer, A., Zimmer, M., Erdmann, K.S., Eulenburg, V., Porthin, A., Heumann, R., Deutsch, U., and Klein, R. (2002). EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Molecular Cell 9: 725-37

fold faq

Year 1999

Palmer, A. and Nebreda, A.R. (1999) “The activation of MAP kinase and p34cdc2/cyclin B during the meiotic maturation of Xenopus oocytes” Progress in Cell Cycle Research, 4 (Meijer L, Jezequel A., du Commun B., eds) Plenum Press, New York, USA.

Ferby, I.; Blazquez, M; Palmer, A., Eritja, R. and Nebreda, A.R. (1999) “A novel p34cdc2 binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes” Genes & Development 13: 2177-89

fold faq

Year 1998

Palmer, A.; Gavin, A.C. and Nebreda,A.R. (1998) "A link between MAP Kinase and p34cdc2/cyclinB during oocyte maturation: p90rsk associates with and phosphorylates the p34cdc2 inhibitory kinase Myt1” EMBO J., 17: 5037-5047.

fold faq

Year 1996

Palmer, A.; Rivett, A.J.; Thomson, S.; Hendil, K.B.; Butcher, G.W.; Fuertes, G. and Knecht, E. (1996)  "Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol" Biochem. J., 316:401-407.

fold faq

Year 1995

Cuervo, A.M.; Palmer, A.; Rivett, A.J. and Knecht, E.(1995) "Degradation of Proteasomes by Lysosomes in Rat Liver" Eur. J. Biochem., 227:792-800.   

fold faq

Year 1994

Palmer, A.; Mason,G.G.F.; Paramio,J.M.; Knecht,E. and Rivett,A.J. (1994) "Changes in Proteasome Localization during the Cell Cycle" Eur. J. Cell Biol., 64:163-175.

fold faq

Year 1993

Rivett, A.J.; Mason; G.G.F.; Djaballah, H.; Savory, P.J.; Palmer, A. and Knecht, E. (1993) "Structure, Activities and Localization of the Rat Liver Multicatalytic Proteinase Complex (Proteasome)" Proteolysis and Protein Turnover (Bond,J.S. & Barret,A.J. eds). Portland Press, London, p. 51-56.

fold faq

Year 1992

Rivett, A.J.; Palmer, A. and Knecht, E. (1992) “Electron microscopic Localization of the multicatalytic Proteinase Complex in Rat Liver and in Cultured Cells" J. Histochem. Cytochem., 40:1165-1172.

fold faq

Year 1991

Knecht, E.; Palmer, A.; Sweeney, S.T. and Rivett, A.J. (1991) "Inmunocytochemical Localization of the Multicatalytic Proteinase in Rat Liver and L-132 Cells" Biochem. Soc. Trans. 19:239S

Interactive

ShareThis
ShareThis