LC-MS Proteomics Specialist (m/f/d)

Max Planck Institute for Brain Research, Frankfurt am Main

Type of Job

Scientist

Neurosciences

Job Code:

Job offer from June 14, 2021

The Max Planck Institute for Brain Research (MPI for Brain Research) in Frankfurt/Main is a vibrant research institution in the field of basic biological and medical research, with a focus on understanding the functions of the brain’s circuits. Our institute has approx. 300 employees in three research departments and five research groups, as well as several service units.

Together with the MPI of Biophysics we operate a joint mass spectrometry lab to develop cutting-edge MS-based methods for projects at both institutes. For this lab, we look for an

Engineer or Research associate (m/f/d) in Chemistry, Biochemistry or Biophysics

as an LC-MS Proteomics Specialist. The position is on an initial, fixed-term contract for two years, with the possibility for extension to a permanent contract.

Your responsibilities:

  • Development of MS-based methods for scientific projects and acquisition, evaluation and analysis of data (label-free (DDA, DIA, iBAQ) & label-based (SILAC, TMT) quantification, targeted proteomics (SRM, PRM), PTM/Phosphoproteomics, low-input proteomics, Top-down analyses, Metabolomics, HDX-MS, MS Imaging.
  • Support and maintenance of LC-MS instruments, routine performance monitoring (calibration, QC measurements), including instrument troubleshooting and front-end cleaning
  • Training of lab members (PhD students and staff)
  • Handling of routine service projects (e.g. gel band analyses, protein identification)

Your profile:

  • Completed university education as Engineer (m/f/d) or Master/Diploma in Chemistry, Biochemistry or Biophysics or equivalent qualification with work experience
  • Comprehensive, hands-on experience using mass spectrometers and nano-H/UHPLC systems is mandatory; experience using Thermo-, Bruker and Waters instruments is advantageous
  • Experience with liquid-handling robotics for automated sample preparation is a plus
  • Knowledge of MS software (Thermo, Bruker, Waters), database search and evaluation software (MaxQuant, Perseus, Proteome Discoverer, PEAKS, Spectronaut) and associated bioinformatics tools (R, Python) is advantageous
  • Excellent knowledge of written and spoken English for evaluation and presentation of scientific data and for exchange with our international colleagues.
  • Open-minded and motivated personality with a focus on teamplay
  • Ability to work accurately and independently as well as excellent communication skills.

We offer:

  • Working on interesting and diverse projects in an internationally leading research environment: biophysics; brain research
  • A friendly working atmosphere with outstanding, state-of-the-art infrastructure including Orbitrap Eclipse (incl. FAIMS) and Fusion Lumos mass spectrometers
  • An initial, fixed-term contract of two years, potentially to be extended to a permanent position
  • Position with payment according to German TVöD (Collective Wage Agreement for Government Service Workers - Federal Government) with all benefits of the public service
  • A corporate pension plan
  • Extensive scientific and personal training programs as well as scientific exchange on workshops and conferences
  • Family service (in-house baby and kids room, on-campus child day care center)
  • Corporate health management (e.g. sports courses)
  • Cafeteria and Bistro in the institute
  • Free parking on institute’s premises

The Max-Planck Society is committed to increase the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.

The compatibility of work and family is very important to us; we offer the possibility of childcare in the kindergarten Kairos close to our institute. Further information can be found on our homepage.

We’re looking forward to receive your application including a letter of motivation explaining how your qualifications and experience make you a good candidate for this job, together with a full CV, reference letters (if available) and related certificates. Please submit your application before August 15th 2021, preferably electronically as a single pdf file on our application platform.

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