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Year 2019

Dalmay T., Abs E., Poorthuis R.B., Hartung J., Pu D., Onasch S., Lozano Y.R., Signoret-Genest J., Gjorgieva J., Letzkus J.J. (2019) A critical role for neocortical processing of threat memory. Neuron, 104:1180-1194. Link

Pardi, M.B., Abs, E., and Letzkus, J.J. (2019). Disinhibition goes spatial. Neuron 101:994-996. Link

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Year 2018

Abs, E., Poorthuis, R.B., Apelblat, D., Muhammad, K., Pardi, M.B., Enke, L., Kushinsky, D., Pu, D.,  Eizinger, M.F., Conzelmann, K.K., Spiegel, I., and Letzkus, J.J. (2018). Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons. Neuron 100: 1-16 pdf

Poorthuis, R.B., Muhammad, K., Wang, M., Verhoog, M.B., Junek, S., Wrana, A., Mansvelder, H.D. and Letzkus, J.J. (2018) Rapid Neuromodulation of Layer 1 Interneurons in Human Neocortex. Cell Reports 23:951-58 pdf

Mager, T., Lopez de la Morena, D., Senn, V., Schlotte, J., D´Errico, A., Feldbauer, K., Wrobel, C., Jung, S., Bodensiek, K., Rankovic, V., Browne, L., Huet, A., Jüttner, J., Wood, P.G., Letzkus, J.J., Moser, T. and Bamberg, E. (2018) High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics. Nature Communications 9:1750 pdf

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Year 2015

Káradóttir R.T., Letzkus, J.J., Mameli, M., Ribeiro, C. (2015). Your ticket to independence: A guide to getting your first principal investigator position. European Journal of Neuroscience 42: 2372-79 pdf

Letzkus, J.J., Wolff, S.B.E. and Lüthi, A. (2015) Disinhibition, a circuit mechanism for associative learning and memory. Neuron 88: 264-276 pdf

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Year 2014

Poorthuis R.B.*, Enke L.*, Letzkus J.J. (2014) Cholinergic circuit modulation through differential recruitment of neocortical interneuron types during behaviour. Journal of Physiology; in press. (*equal contribution) pdf

Senn, V., Wolff, S.B., Herry, C., Grenier, F., Ehrlich, I., Gründemann, J., Fadok, J.P., Müller, C., Letzkus, J.J., Lüthi, A. (2014) Long-range connectivity defines behavioral specificity of amygdala neurons. Neuron; 81; 428-37. pdf

Wolff, S.B., Gründemann, J., Tovote, P., Krabbe, S., Jacobson, G.A., Müller, C., Herry, C., Ehrlich, I., Friedrich, R.W., Letzkus, J.J.*, Lüthi, A.* (2014) Amygdala interneuron subtypes control fear learning through disinhibition. Nature; 509, 453–458. (*equal contribution) pdf

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Year 2011

Letzkus, J.J., Wolff, S.B.E., Meyer, E.M.M., Tovote, P., Courtin, J., Herry, C., Lüthi, A. (2011) A disinhibitory microcircuit for associative fear learning in auditory cortex. Nature; 480; 331-335. pdf Supplementary information

Kampa, B.M., Gundlfinger, A., Letzkus, J.J., Leibold, C. (2011) Editorial for special issue: ‘Circuit mechanisms of memory formation’. Neural Plasticity 2011; 494675. pdf

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Year 2010

Ciocchi, S., Herry, C., Grenier, F., Wolff, S.B.E., Letzkus, J.J., Vlachos, I., Ehrlich, I., Sprengel, R., Deisseroth, K., Stadler, M.B., Müller, C., Lüthi, A. (2010) Encoding of conditioned fear in central amygdala inhibitory circuits. Nature; 468; 277-282. pdf Supplementary information

Froemke, R.C., Letzkus, J.J., Kampa, B.M., Hang, G.B., Stuart, G.J. (2010) Dendritic synapse location and neocortical spike-timing-dependent plasticity. Frontiers in Synaptic Neuroscience; 2; 29; 1-14. pdf

Herry, C., Ferraguti, F., Singewald, N., Letzkus, J.J., Ehrlich, I., Luthi, A. (2010) Neuronal circuits of fear extinction. European Journal of Neuroscience; 31; 599-612. pdf

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Year 2008

Letzkus J.J. and Stuart G.J. (2008) All asleep - but inhibition is wide awake. Neuron; 57; 804-806. pdf

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Year 2007

Kampa, B.M., Letzkus, J.J., Stuart, G.J. (2007) Dendritic mechanisms controlling spike-timing dependent synaptic plasticity. Trends in Neurosciences 30; 456-463. pdf

Kole M.H.*, Letzkus J.J.*, Stuart G.J. (2007) Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy. Neuron 55; 633-647. (*equal contribution) pdf Supplementary information

Letzkus, J.J., Kampa, B.M., Stuart, G.J. (2007) Does spike-timing-dependent synaptic plasticity underlie memory formation? Clinical and Experimental Pharmacology and Physiology 34; 1070-1076. pdf

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Year 2006

Kampa, B.M., Letzkus, J.J., Stuart, G.J. (2006) Cortical feed-forward networks for binding different streams of sensory information. Nature Neuroscience 9 (12); 1472-73. pdf Supplementary information

Letzkus, J.J., Kampa, B.M., Stuart, G.J. (2006) Learning rules for spike timing-dependent plasticity depend on dendritic synapse location. Journal of Neuroscience 26; 10420-29. pdf Supplementary information

Davie, J.T., Kole, M.H.P., Letzkus, J.J., Rancz, E.A., Spruston, N., Stuart, G.J., Hausser, M. (2006) Dendritic patch-clamp recording. Nature Protocols 1 (3); 1235-47. pdf

Kampa, B.M., Letzkus, J.J., Stuart, G.J. (2006) Requirement of dendritic calcium spikes for induction of spike-timing-dependent synaptic plasticity. Journal of Physiology (London) 574; 283-90. pdf Supplementary information

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Year 2004

Kuppers-Munther, B., Letzkus, J.J., Luer, K., Technau, G., Schmidt, H., Prokop, A. (2004) A new culturing strategy optimises Drosophila primary cell cultures for structural and functional analyses. Developmental Biology 269 (2); 459-78. pdf

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Year 2003

Kuppers B., Sanchez-Soriano N., Letzkus J., Technau G.M., Prokop A. (2003) In developing Drosophila neurones the production of gamma-amino butyric acid is tightly regulated downstream of glutamate decarboxylase translation and can be influenced by calcium. Journal of Neurochemistry 84 (5); 939-51. pdf