Publications of B. Laube

Haeger, S.; Lang, N.; Laube, B.; Betz, H.; Schmalzing, G.: A C terminal amphipathic motif plays a crucial role in the assembly of homopentameric alpha 1 glycine receptors. Naunyn-Schmiedebergs Archives of Pharmacology 369 (Suppl. Suppl. 1), p. R20 - R20 (2004)

Lang, N.; Laube, B.; Sadtler, S.; Braam, U.; Schuler, T.; Betz, H.; Schmalzing, G.: An acidic and a phenylalanine motif facilitate exit of glycine receptors from the endoplasmic reticulum. Naunyn-Schmiedebergs Archives of Pharmacology 369 (Suppl. Suppl. 1), p. R21 - R21 (2004)

Laube, B.; Betz, H.: Glycine receptors. Encyclopedia of Biological Chemistry 2, pp. 237 - 243 (2004)

Laube, B.; Schemm, R.; Betz, H.: Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor. Neuropharmacology 47 (7), pp. 994 - 1007 (2004)

O'Shea, S. M.; Becker, L.; Weiher, H.; Betz, H.; Laube, B.: Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice. Journal of Neuroscience 24 (9), pp. 2322 - 2327 (2004)

Betz, H.; Laube, B.; Schemm, R.; Grudzinska, J.; Kneussel, M.; Fuhrmann, J.; O'Sullivan, G.: Neurotransmitter-gated chloride channels in postsynaptic membranes. Journal of General Physiology 122 (1), p. 7A - 7A (2003)

Ortinau, S.; Laube, B.; Zimmermann, H.: ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity. Journal of Neuroscience 23 (12), pp. 4996 - 5003 (2003)

Betz, H.; Kneussel, M.; Fuhrmann, J.; Grosskreutz, Y.; Laube, B.; O'Sullivan, G.; Ohno, K.; Gomeza, J.; Far, O. E.: Assembly of inhibitory synapses. Journal of Neurochemistry 85 (Suppl. Suppl. 1), p. 95 - 95 (2003)

Lang, N.; Sadtler, S.; Laube, B.; Betz, H.; Schmalzing, G.: Identification of a cytosolic motif crucial for the ER exit of the homopentameric alpha 1 glycine receptor. Naunyn-Schmiedebergs Archives of Pharmacology 367 (Suppl. Suppl. 1), p. R37 - R37 (2003)

Foucaud, B.; Laube, B.; Schemm, R.; Kreimeyer, A.; Goeldner, M.; Betz, H.: Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling. Journal of Biological Chemistry 278 (26), pp. 24011 - 24017 (2003)

Gomeza, J.; Ohno, K.; Hulsmann, S.; Armsen, W.; Eulenburg, V.; Richter, D. W.; Laube, B.; Betz, H.: Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality. Neuron 40 (4), pp. 797 - 806 (2003)

Ortenau, S.; Laube, B.; Zimmermann, H.: Inhibition of NMDA receptors by ATP rescues cultured hippocampal neurons from NMDA-mediated neurotoxicity. Journal of Neuroscience 23, pp. 4996 - 5003 (2003)

Sadtler, S.; Laube, B.; Lashub, A.; Nicke, A.; Betz, H.; Schmalzing, G.: A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha 1 subunit. Journal of Biological Chemistry 278 (19), pp. 16782 - 16790 (2003)

Laube, B.: Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X(2) and postsynaptic glycine receptors. European Journal of Neuroscience 16 (6), pp. 1025 - 1036 (2002)

Laube, B.; Maksay, G.; Schemm, R.; Betz, H.: Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses? Trends in Pharmacological Sciences 23 (11), pp. 519 - 527 (2002)

Leyendecker, A.; Sadtler, S.; Laube, B.; Betz, H.; Schmalzing, G.: Localisation of a proteolysis site on the glycine receptor alpha 2 subunit by methionine scanning mutagenesis. Naunyn-Schmiedebergs Archives of Pharmacology 365 (Suppl. 1), p. 65 - 65 (2002)

Maksay, G.; Biró, T.; Laube, B.: Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics. Biochemical Pharmacology 64 (2), pp. 285 - 288 (2002)

Ortinau, S.; Laube, B.; Zimmermann, H.: ATP rescues cultured hippocampal neurons from NMDA-mediated neurotoxicity by direct inhibition of NMDA receptors. Drug Development Research 56 (4), p. 132 - 132 (2002)

Perret, P.; Laube, B.; Schemm, R.; Betz, H.; Goeldner, M.; Foucaud, B.: Affinity labeling of cysteine-mutants evidences contact residues in modeled receptor binding sites. Journal of Receptor and Signal Transduction Research 22 (1-4), pp. 345 - 356 (2002)

Sadtler, S.; Leyendecker, A.; Laube, B.; Betz, H.; Schmalzing, G.: Ubiquitination and Y339 are involved in internalisation of the homomeric alpha 1 glycine receptor. Naunyn-Schmiedebergs Archives of Pharmacology 365 (Suppl. 1), p. 64 (2002)