Neurovascular interface - Acker-Palmer Group

The development of the nervous and the vascular systems exhibit extensive similarities, both on the anatomical and the molecular level. Blood vessels and nerves are structurally similar and often aligned, following parallel routes. The brain is the most vascularized tissue in our body. It is now believed that blood vessels in the brain exert instructive functions that go beyond supplying nutrients and oxygen, for example supplying ligands that directly influence neuronal behavior by activating corresponding receptors and signaling pathways in neuronal cells. We are interested in elucidating the molecular pathways involved in the crosstalk between vessels and nerves and how this crosstalk signaling is integrated among the different cellular players (neurons, endothelial cells, astrocytes) at the neurovascular interface. We focus on the role of vessels during the development of the nervous system but also in the adult during synaptic plasticity using both mouse and zebrafish models.

Amparo Acker-Palmer is a Max Planck Fellow at the MPI for Brain Research since July 1, 2014.



Upcoming Lectures and Events

04 March 2021

mpibr External Postdoctoral Seminar Concatenations by Heike Blockus (Columbia University (New York)

Title: Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocamp... [more]

10 March 2021

Neuroscience Online Lecture by Ilaria Testa (Advanced Optical Bio-Imaging Laboratory Science for Life Laboratory, KTH Karolinska Institutet Science Park, Stockholm)

Title: A new look in the interior of cells with 3D MoNaLISA nanoscopy [more]

30 March 2021

Connecting Brains Lecture by André Fenton (New York University, New York, USA)

Title: Learning to Learn, across biological scales [more]

31 March 2021

Neuroscience Lecture by Emily Osterweil (Centre for Discovery Brain Sciences University of Edinburgh)

Title: The long and short of altered translation in Fragile X [more]

07 April 2021

Neuroscience Online Lecture by Naoshige Uchida (Center for Brain Science, Harvard University Cambridge, USA)

Title: Diversity of dopamine neurons: multiple axes and vector prediction errors [more]